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1

An efficient palladium catalyzed synthesis of 2-arylbenzothiazoles

Vattoly J. Majo, Jaya Prabhakaran, J.John Mann, J.S. Dileep Kumar

Journal:

Tetrahedron Letters

Year:

2003

Language:

english

File:

PDF, 194 KB

english, 2003

2

Facile Palladium-Catalyzed Synthesis of 3-Arylpyrazolo[1,5-a]pyrimidines

Vattoly J. Majo, Jaya Prabhakaran, J. John Mann, J. S. Dileep Kumar

Journal:

Advanced Synthesis & Catalysis

Year:

2003

Language:

english

File:

PDF, 85 KB

english, 2003

3

ChemInform Abstract: Intramolecular Cyclization of Azides by Iminium Species. A Novel Method for the Construction of Nitrogen Heterocycles under Vilsmeier Conditions.

Vattoly J. Majo, Paramasivan T. Perumal

Journal:

Year:

1999

File:

PDF, 34 KB

1999

4

ChemInform Abstract: The Unexpected Formation of Bicyclo[2.2.1]heptane Derivatives by Lewis Acid Catalyzed Transannular Double Cyclization.

Vattoly J. Majo, Shuichi Suzuki, Masahiro Toyota, Masataka Ihara

Journal:

Year:

2001

File:

PDF, 36 KB

2001

5

ChemInform Abstract: A Facile Synthesis of Bridged Bicycloalkenones from Enol Silanes of Medium and Large Rings by Palladium(II) Mediated Cycloalkenylation Reaction.

Masahiro Toyota, Vattoly J. Majo, Masataka Ihara

Journal:

Year:

2001

File:

PDF, 30 KB

2001

6

Facile Palladium-Catalyzed Synthesis of 3-Arylpyrazolo[1,5-a]pyrimidines.

Vattoly J. Majo, Jaya Prabhakaran, J. John Mann, J. S. Dileep Kumar

Journal:

Year:

2003

File:

PDF, 95 KB

2003

7

An Efficient Palladium-Catalyzed Synthesis of 2-Arylbenzothiazoles.

Vattoly J. Majo, Jaya Prabhakaran, J. John Mann, J. S. Dileep Kumar

Journal:

Year:

2004

File:

PDF, 88 KB

2004

8

Synthesis of [O-Methyl-11C] 1-(2-chlorophenyl)-5- (4-methoxyphenyl)-4-methyl-1H-pyrazole-3-carboxylic Acid Piperidin-1-ylamide: A Potential PET Ligand for CB1 Receptors.

J. S. Dileep Kumar, Jaya Prabhakaran, Victoria Arango, Ramin V. Parsey, Mark D. Underwood, Norman R. Simpson, Suham A. Kassir, Vattoly J. Majo, Ronald L. Van Heertum, J. John Mann

Journal:

Year:

2004

File:

PDF, 92 KB

2004

9

Chiral synthesis of (2S,3S)-2-(2-morpholin-2-yl-2-phenylmethoxy)phenol

Jaya Prabhakaran, Vattoly J. Majo, J. John Mann, J. S. Dileep Kumar

Journal:

Year:

2004

Language:

english

File:

PDF, 137 KB

english, 2004

10

Synthesis of [11C]celecoxib: a potential PET probe for imaging COX-2 expression

Jaya Prabhakaran, Vattoly J. Majo, Norman R. Simpson, Ronald L. Van Heertum, J. John Mann, J. S. Dileep Kumar

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2005

Language:

english

File:

PDF, 121 KB

english, 2005

11

Synthesis and in vivo evaluation of [O-methyl-11C] 2-(4-methoxyphenyl)-N-(4-methylbenzyl)-N-(1-methyl- piperidin-4-yl)acetamide as an imaging probe for 5-HT2A receptors

Jaya Prabhakaran, Ramin V. Parsey, Vattoly J. Majo, Ronald L. Van Heertum, J. John Mann, J. S. Dileep Kumar

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2006

Language:

english

File:

PDF, 224 KB

english, 2006

12

Synthesis and evaluation of [O-methyl-11C]4-[3-[4-(2-methoxyphenyl)- piperazin-1-yl]propoxy]-4-aza-tricyclo[5.2.1.02,6]dec-8-ene-3,5-dione as a 5-HT1A receptor agonist PET ligand

Vattoly J. Majo, Ramin V. Parsey, Jaya Prabhakaran, J. John Mann, J. S. Dileep Kumar

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2008

Language:

english

File:

PDF, 189 KB

english, 2008

13

Synthesis of [N-methyl-11C]-3-[(6-dimethylamino)pyridin-3-yl]-2,5-dimethyl-N, N-dipropylpyrazolo[1,5-a]pyrimidine-7-amine: A potential PET ligand for in vivo imaging of CRF1 receptors

J.S. Dileep Kumar, Vattoly J. Majo, Jaya Prabhakaran, Norman R. Simpson, Ronald L. Van Heertum, J. John Mann

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2003

Language:

english

File:

PDF, 138 KB

english, 2003

14

Synthesis of [O-methyl-11C]-4-(1,3-dimethoxy-2-propylamino)-2,7-dimethyl-8-(2,4-dichlorophenyl)[1,5-a]pyrazolo-1,3,5-triazine ([11C]DMP696): a potential PET ligand for CRF1 receptors

J. S. Dileep Kumar, Vattoly J. Majo, Norman R. Simpson, Jaya Prabhakaran, Ronald L. Van Heertum, J. John Mann

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2004

Language:

english

File:

PDF, 96 KB

english, 2004

15

Dimerization of substituted 2-aminobenzoic acids under Vilsmeier conditions: A novel route to the synthesis of 4-(3H)-quinazolinones

Vattoly J Majo, Paramasivan T Perumal

Journal:

Tetrahedron Letters

Year:

1996

Language:

english

File:

PDF, 164 KB

english, 1996

16

Synthesis and in vivo evaluation of [11C]SN003 as a PET ligand for CRF1 receptors

J.S. Dileep Kumar, Vattoly J. Majo, Gregory M. Sullivan, Jaya Prabhakaran, Norman R. Simpson, Ronald L. Van Heertum, J. John Mann, Ramin V. Parsey

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 173 KB

english, 2006

17

Synthesis and in vivo evaluation of [18F]-4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide as a PET imaging probe for COX-2 expression

Jaya Prabhakaran, Mark D. Underwood, Ramin V. Parsey, Victoria Arango, Vattoly J. Majo, Norman R. Simpson, Ronald Van Heertum, J. John Mann, J.S. Dileep Kumar

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 412 KB

english, 2007

18

Synthesis of [O-methyl-11C]1-(2-chlorophenyl)-5-(4-methoxyphenyl)-4-methyl-1H-pyrazole-3-carboxylic acid piperidin-1-ylamide: a potential PET ligand for CB1 receptors

J.S.Dileep Kumar, Jaya Prabhakaran, Victoria Arango, Ramin V. Parsey, Mark D. Underwood, Norman R. Simpson, Suham A. Kassir, Vattoly J. Majo, Ronald L. Van Heertum, J.John Mann

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 388 KB

english, 2004

19

A general method for the synthesis of aryl [11C]methylsulfones: Potential PET probes for imaging cyclooxygenase-2 expression

Vattoly J. Majo, Jaya Prabhakaran, Norman R. Simpson, Ronald L. Van Heertum, J. John Mann, J.S. Dileep Kumar

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 128 KB

english, 2005

20

Synthesis and in vivo evaluation of [11C]MPTQ: A potential PET tracer for alpha2A-adrenergic receptors

Jaya Prabhakaran, Vattoly J. Majo, Matthew S. Milak, Pratap Mali, Lyudmila Savenkova, J. John Mann, Ramin V. Parsey, J.S. Dileep Kumar

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 380 KB

english, 2010

21

Synthesis, in vitro and in vivo evaluation of [11C]MMTP: A potential PET ligand for mGluR1 receptors

Jaya Prabhakaran, Vattoly J. Majo, Matthew S. Milak, Suham A. Kassir, Mikael Palner, Lyudmila Savenkova, Pratap Mali, Victoria Arango, J. John Mann, Ramin V. Parsey, J.S. Dileep Kumar

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 427 KB

english, 2010

22

A facile synthesis of bridged bicycloalkenones from enol silanes of medium and large rings by palladium(II) mediated cycloalkenylation reaction

Masahiro Toyota, Vattoly J Majo, Masataka Ihara

Journal:

Tetrahedron Letters

Year:

2001

Language:

english

File:

PDF, 65 KB

english, 2001

23

The Vilsmeier cyclization of azides. Synthesis of oxazoles and vinyl azides from 2-azidoacetophenones

Vattoly J. Majo, Paramasivan T. Perumal

Journal:

Tetrahedron Letters

Year:

1997

Language:

english

File:

PDF, 218 KB

english, 1997

24

In vivo assessment of [11C]MRB as a prospective PET ligand for imaging the norepinephrine transporter

Alin J. Severance, Matthew S. Milak, J. S. Dileep Kumar, Jaya Prabhakaran, Vattoly J. Majo, Norman R. Simpson, Ronald L. Van Heertum, Victoria Arango, J. John Mann, Ramin V. Parsey

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2007

Language:

english

File:

PDF, 262 KB

english, 2007

25

Synthesis and in vivo evaluation of a novel 5-HT1Areceptor agonist radioligand [O-methyl-11C]2-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-4-methyl-1,2,4-triazine-3,5(2H,4H)dione in nonhuman primates

J. S. Dileep Kumar, Jaya Prabhakaran, Vattoly J. Majo, Matthew S. Milak, Shu-Chi Hsiung, Hadassah Tamir, Norman R. Simpson, Ronald L. Van Heertum, J. John Mann, Ramin V. Parsey

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2007

Language:

english

File:

PDF, 363 KB

english, 2007

26

Synthesis, in vitro and in vivo evaluation of [O-methyl-11C] 2-{4-[4-(3-methoxyphenyl)piperazin-1-yl]-butyl}-4-methyl-2H-[1,2,4]-triazine-3,5-dione: A novel agonist 5-HT1A receptor PET ligand

Jaya Prabhakaran, Ramin V. Parsey, Vattoly J. Majo, Shu-Chi Hsiung, Matthew S. Milak, Hadassah Tamir, Norman R. Simpson, Ronald L. Van Heertum, J. John Mann, J.S. Dileep Kumar

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 200 KB

english, 2006

27

In vivo serotonin-sensitive binding of [11C]CUMI-101: a serotonin 1A receptor agonist positron emission tomography radiotracer

Milak, Matthew S, Severance, Alin J, Prabhakaran, Jaya, Kumar, J S Dileep, Majo, Vattoly J, Ogden, R Todd, Mann, J John, Parsey, Ramin V

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2010

Language:

english

File:

PDF, 379 KB

english, 2010

28

Synthesis and in vivo evaluation of [O-methyl-11C] N-[3,5-dichloro-2-(methoxy)phenyl]-4-(methoxy)-3-(1-piperazinyl)benzenesulfonamide as an imaging probe for 5-HT6 receptors

Fei Liu, Vattoly J. Majo, Jaya Prabhakaran, Matthew S. Milak, J. John Mann, Ramin V. Parsey, J.S. Dileep Kumar

Journal:

Bioorganic & Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 414 KB

english, 2011

29

Radiosynthesis of [11C]BBAC and [11C]BBPC as potential PET tracers for orexin2 receptors

Fei Liu, Vattoly J. Majo, Jaya Prabhakaran, John Castrillion, J. John Mann, Diana Martinez, J.S. Dileep Kumar

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 388 KB

english, 2012

30

Intramolecular Cyclization of Azides by Iminium Species. A Novel Method for the Construction of Nitrogen Heterocycles under Vilsmeier Conditions

Majo, Vattoly J., Perumal, Paramasivan T.

Journal:

Journal of Organic Chemistry

Year:

1998

Language:

english

File:

PDF, 207 KB

english, 1998

31

Synthesis and in vitro evaluation of [18F](R)-FEPAQ: A potential PET ligand for VEGFR2

Jaya Prabhakaran, Victoria Arango, Vattoly J. Majo, Norman R. Simpson, Suham A. Kassir, Mark D. Underwood, Hanish Polavarapu, Jeffrey N. Bruce, Peter Canoll, J. John Mann, J.S. Dileep Kumar

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 235 KB

english, 2012

32

Synthesis and in vivo evaluation of [O-methyl-11C](2R,4R)-4-hydroxy-2-[2-[2-[2-(3-methoxy)phenyl]ethyl]phenoxy]ethyl-1-methylpyrrolidine as a 5-HT2A receptor PET ligand

J.S. Dileep Kumar, Jaya Prabhakaran, Kjell Erlandsson, Vattoly J. Majo, Norman R. Simpson, Mali Pratap, Ronald L. Van Heertum, J. John Mann, Ramin V. Parsey

Journal:

Nuclear Medicine and Biology

Year:

2006

Language:

english

File:

PDF, 376 KB

english, 2006

33

In vitro and in vivo evaluation of [11C]MPEPy as a potential PET ligand for mGlu5 receptors

Alin J. Severance, Ramin V. Parsey, J.S. Dileep Kumar, Mark D. Underwood, Victoria Arango, Vattoly J. Majo, Jaya Prabhakaran, Norman R. Simpson, Ronald L. Van Heertum, J. John Mann

Journal:

Nuclear Medicine and Biology

Year:

2006

Language:

english

File:

PDF, 383 KB

english, 2006

34

One-Pot Synthesis of Heterocyclic β-Chlorovinyl Aldehydes Using Vilsmeier Reagent

Majo, Vattoly J., Perumal, Paramasivan T.

Journal:

Journal of Organic Chemistry

Year:

1996

Language:

english

File:

PDF, 146 KB

english, 1996

35

Synthesis and in Vivo Validation of [ O -Methyl- 11 C]2-{4-[4-(7-methoxynaphthalen-1-yl)piperazin- 1-yl]butyl}-4-methyl-2 H -[1,2,4]triazine-3,5-dione: A Novel 5-HT 1A Receptor Agonist Positron Emission Tomography Ligand

Kumar, J. S. Dileep, Majo, Vattoly J., Hsiung, Shu-Chi, Millak, Matthew S., Liu, Kuo-Peing, Tamir, Hadassah, Prabhakaran, Jaya, Simpson, Norman R., Van Heertum, Ronald L., Mann, J. John, Parsey, Ramin

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 318 KB

english, 2006

36

PET and SPECT tracers for glutamate receptors

Majo, Vattoly J., Prabhakaran, Jaya, Mann, J. John, Kumar, J.S. Dileep

Journal:

Drug Discovery Today

Year:

2013

Language:

english

File:

PDF, 563 KB

english, 2013

37

Synthesis and in vitro evaluation of [18F]BMS-754807: A potential PET ligand for IGF-1R

Majo, Vattoly J., Arango, Victoria, Simpson, Norman R., Prabhakaran, Jaya, Kassir, Suham A., Underwood, Mark D., Bakalian, Mihran, Canoll, Peter, John Mann, J., Dileep Kumar, J.S.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 494 KB

english, 2013

38

Synthesis and in vivo evaluation of [18F]2-(4-(4-(2-(2-fluoroethoxy)phenyl)piperazin-1-yl)butyl)-4-methyl-1,2,4-triazine-3,5(2H,4H)-dione ([18F]FECUMI-101) as an imaging probe for 5-HT1A receptor agonist in nonhuman primates

Majo, Vattoly J., Milak, Matthew S., Prabhakaran, Jaya, Mali, Pratap, Savenkova, Lyudmila, Simpson, Norman R., Mann, J. John, Parsey, Ramin V., Kumar, J. S. Dileep

Journal:

Bioorganic & Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 1.17 MB

english, 2013

39

Autoradiographic evaluation of [3H]CUMI-101, a novel, selective 5-HT1AR ligand in human and baboon brain

Kumar, J.S. Dileep, Parsey, Ramin V., Kassir, Suham A., Majo, Vattoly J., Milak, Matthew S., Prabhakaran, Jaya, Simpson, Norman R., Underwood, Mark D., Mann, J. John, Arango, Victoria

Journal:

Year:

2013

Language:

english

File:

PDF, 1.05 MB

english, 2013

40

Synthesis and evaluation of arylpiperazines derivatives of 3,5-dioxo-(2H,4H)-1,2,4-triazine as 5-HT1AR ligands

Kumar, J.S. Dileep, Majo, Vattoly J., Prabhakaran, Jaya, Mann, J. John

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 433 KB

english, 2014

41

The unexpected formation of bicyclo[2.2.1]heptane derivatives by Lewis acid-catalyzed transannular double cyclization

Majo, Vattoly J., Suzuki, Shuichi, Toyota, Masahiro, Ihara, Masataka

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

2000

Language:

english

File:

PDF, 150 KB

english, 2000

42

Autoradiographic Evaluation of [ 18 F]FECUMI-101, a High Affinity 5-HT 1A R Ligand in Human Brain

Kumar, J. S. Dileep, Underwood, Mark D., Simpson, Norman R., Kassir, Suham A., Prabhakaran, Jaya, Majo, Vattoly J., Bakalian, Mihran J., Parsey, Ramin V., Mann, J. John, Arango, Victoria

Journal:

ACS Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 1.16 MB

english, 2016

43

Radiosynthesis of [ 18 F]ATPFU: a potential PET ligand for mTOR

Majo, Vattoly J., Simpson, Norman R., Prabhakaran, Jaya, Mann, J. John, Kumar, J. S. Dileep

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2014

Language:

english

File:

PDF, 646 KB

english, 2014

44

Comparison of High and Low Affinity Serotonin 1A Receptors by PET In Vivo in Nonhuman Primates

Kumar, J.S. Dileep, Milak, Matthew S., Majo, Vattoly J., Prabhakaran, Jaya, Mali, Pratap, Savenkova, Lyudmila, Mann, J. John, Parsey, Ramin V.

Journal:

Journal of Pharmacological Sciences

Year:

2012

Language:

english

File:

PDF, 213 KB

english, 2012

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